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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITGA4
All Species:
25.76
Human Site:
Y1009
Identified Species:
47.22
UniProt:
P13612
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13612
NP_000876.3
1032
114872
Y1009
A
G
F
F
K
R
Q
Y
K
S
I
L
Q
E
E
Chimpanzee
Pan troglodytes
XP_525977
1032
114817
Y1009
A
G
F
F
K
R
Q
Y
K
S
I
L
Q
E
E
Rhesus Macaque
Macaca mulatta
XP_001100929
1032
114958
Y1009
A
G
F
F
K
R
Q
Y
K
S
I
L
Q
E
E
Dog
Lupus familis
XP_545551
1165
128321
Y1141
A
G
F
F
K
R
Q
Y
K
S
I
L
Q
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q00651
1039
115677
Y1016
A
G
F
F
K
R
Q
Y
K
S
I
L
Q
E
E
Rat
Rattus norvegicus
Q63258
1135
124176
E1070
F
K
R
A
K
H
P
E
A
T
V
P
Q
Y
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515892
940
104353
Y918
A
G
F
F
K
R
Q
Y
K
A
I
H
Q
D
E
Chicken
Gallus gallus
P26008
1034
114370
R1011
M
G
F
F
K
R
V
R
P
P
Q
E
E
Q
E
Frog
Xenopus laevis
Q91687
1032
115197
Y1007
V
G
F
F
R
R
K
Y
Q
P
I
G
T
E
E
Zebra Danio
Brachydanio rerio
XP_002663459
1018
113210
F995
T
L
W
K
L
G
F
F
K
R
T
L
K
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24247
1146
127955
R1116
V
G
F
F
K
R
I
R
P
T
D
P
T
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34446
1226
135921
R1186
C
G
F
F
K
R
N
R
P
P
T
E
H
A
E
Sea Urchin
Strong. purpuratus
XP_794080
1226
134761
P1197
Q
N
R
R
G
R
Q
P
P
Y
T
Q
S
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97
75.1
N.A.
84.1
25.8
N.A.
65.5
26.2
54.4
47.6
N.A.
24
N.A.
22.1
24.7
Protein Similarity:
100
99.9
98.4
81.7
N.A.
91.8
44.4
N.A.
77.5
46.6
74.1
65.3
N.A.
43.4
N.A.
41.3
42.9
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
80
40
53.3
20
N.A.
33.3
N.A.
40
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
93.3
53.3
73.3
46.6
N.A.
40
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
0
0
8
0
0
0
0
8
8
0
0
0
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
16
8
54
70
% E
% Phe:
8
0
77
77
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
77
0
0
8
8
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
8
8
0
8
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
54
0
0
0
0
% I
% Lys:
0
8
0
8
77
0
8
0
54
0
0
0
8
0
8
% K
% Leu:
0
8
0
0
8
0
0
0
0
0
0
47
0
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
8
31
24
0
16
0
0
0
% P
% Gln:
8
0
0
0
0
0
54
0
8
0
8
8
54
16
0
% Q
% Arg:
0
0
16
8
8
85
0
24
0
8
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
39
0
0
8
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
16
24
0
16
0
0
% T
% Val:
16
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _